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Yet, although GLP-1RA is more expensive than other glucose-lowering agents, recent cost-effectiveness analyses suggest that in US patients with T2D and a CVD-related hospitalization, the added medical cost of treatment with GLP-1RAs is offset by lower inpatient and outpatient care costs, resulting in budget neutrality against standard of care (Evans et al
No Synthetic Precursors
CASE OPTION:CASED
59 Compared to human GLP-1 (Figure 1A), the alanine residue at the second position of the N-terminus in GLP-1 RAs and a dual GLP-1/GIP RA (except for liraglutide) has been substituted to prevent metabolism by DPP-4 (Figure 1)
